Women with Interstitial Cystitis or Painful Bladder Syndrome have other conditions such as irritable bowel syndrome and fibromyalgia

"Many women with IC/PBS have other conditions such as irritable bowel syndrome and fibromyalgia. Scientists believe IC/PBS may be a bladder manifestation of a more general condition that causes inflammation in various organs and parts of the body."


source:http://kidney.niddk.nih.gov/kudiseases/pubs/interstitialcystitis/#cause

Stresses (including 'social subordination') increase serotonin and cortisol and result in 'less exploratory' and less 'spontaneous' behaviour

http://www.cnr.uidaho.edu/fish511/Readings/Readings%202010/nsl230.pdf

Boron causes elevation in estrogen (17 beta-estradiol) and testosterone, reduction in urinary excretion of magnesium and calcium, increases plasma copper, SOD, and ceruloplasmin, (the last three are also raised by estrogen therapy, but by a lesser degree is boron is insufficient), and "it is possible that high dietary intakes of boron or molybdenum could regulate the rate of catabolism, or even the metabolic fate of the major estrogens." (i.e., could prevent methylation of estrogen by COMT)

sources:
http://www.nlm.nih.gov/medlineplus/druginfo/natural/894.html
http://www.ncbi.nlm.nih.gov/pubmed/3678698
http://www.ithyroid.com/boron.htm

Boswellia caused a reversal in brain metastasis - the anti-cancer potential of boswellia serrata

source: http://www.pinestreetfoundation.org/avenues/avenues1920/stritter1920.html

"Subsequently, Dr. Flavin has had two more women with brain metastases greatly improve using the same regimen. Reportedly, Harvard's Dana Farber Cancer Center is seeking approval for a clinical trial to study boswellia use in this setting."

"BOSWELLIA USE IN BRAIN METASTASES

Last year, Dr. Dana Flavin at the Foundation for Collaborative Medicine and Research in Greenwich, CT, reported on a remarkable case of a woman with breast cancer whose multiple brain metastases showed no improvement after two weeks of Xeloda and brain radiation.2 She was then started on boswellia 800 mg three times a day. (Boswellia, also known as Indian frankincense, is an herbal supplement with anti-inflammatory properties and is generally available through retail and online health food stores.) Ten weeks later, a repeat brain CT showed complete resolution of the brain metastases. Impressively, she has been maintained on boswellia for the past four years with no recurrent brain metastasis.

Subsequently, Dr. Flavin has had two more women with brain metastases greatly improve using the same regimen. Reportedly, Harvard's Dana Farber Cancer Center is seeking approval for a clinical trial to study boswellia use in this setting."